Levels of 8-OxodG Predict Hepatobiliary Pathology in Opisthorchis viverrini Endemic Settings in Thailand.

Opisthorchis viverrini is distinct among helminth infections as it drives a chronic inflammatory response in the intrahepatic bile duct that progresses from advanced periductal fibrosis (APF) to cholangiocarcinoma (CCA). Extensive research shows that oxidative stress (OS) plays a critical role in th...

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Main Authors: Prasert Saichua, Anna Yakovleva, Christine Kamamia, Amar R Jariwala, Jiraporn Sithithaworn, Banchob Sripa, Paul J Brindley, Thewarach Laha, Eimorn Mairiang, Chawalit Pairojkul, Narong Khuntikeo, Jason Mulvenna, Paiboon Sithithaworn, Jeffrey M Bethony
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4521778?pdf=render