Detoxification of Hyperglycemia-induced Glucose Toxicity by the Hexosamine Biosynthetic Pathway

Detoxification of Hyperglycemia-induced Glucose Toxicity by the Hexosamine Biosynthetic Pathway

The abnormal intermediate glucose metabolic pathways induced by elevated intracellular glucose levels during hyperglycemia often establish the metabolic abnormality that leads to cellular and structural changes in development and to progression of diabetic pathologies. Glucose toxicity generally ref...

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Bibliographic Details
Main Authors: Andrew Jun Wang, Aimin Wang, Vincent Hascall
Format: Article
Language:English
Published: IMR Press 2024-02-01
Series:Frontiers in Bioscience-Landmark
Subjects:
hyperglycemia
hexosamine biosynthetic pathway
intracellular hyaluronan
o-glycosylation
glucose toxicity
heparin
hep-tri
4mu-xyloside
diabetic nephropathy
Online Access:https://www.imrpress.com/journal/FBL/29/2/10.31083/j.fbl2902071

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https://www.imrpress.com/journal/FBL/29/2/10.31083/j.fbl2902071

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