Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus

Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus

The human ribosomal DNA (rDNA) copy number (CN) has been challenging to analyse, and its sequence has been excluded from reference genomes due to its highly repetitive nature. The 45S rDNA locus encodes essential components of the cell, nevertheless rDNA displays high inter-individual CN variation t...

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Bibliographic Details
Main Authors: Aleem Razzaq, Yosra Bejaoui, Tanvir Alam, Mohamad Saad, Nady El Hajj
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Epigenetics
Subjects:
ribosomal dna
copy number
dna methylation
autism spectrum disorder
schizophrenia
dosage compensation
Online Access:http://dx.doi.org/10.1080/15592294.2023.2229203

Internet

http://dx.doi.org/10.1080/15592294.2023.2229203

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