Effect of Antimalarial Drugs on Plasmodia Cell-Free Protein Synthesis

A cell-free system from Plasmodium falciparum able to translate endogenous mRNA was used to determine the effect of artemisinin, chloroquine and primaquine on the protein synthesis mechanism of the parasite. The antimalarial drugs did not inhibit the incorporation of [³H] methionine into parasite pr...

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Bibliographic Details
Main Authors: Ana Ferreras, Ledia Triana, Erlinda Sánchez, Flor Herrera
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2002-04-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000300018