Periods of high dengue transmission defined by rainfall do not impact efficacy of dengue vaccine in regions of endemic disease.

Periods of high dengue transmission defined by rainfall do not impact efficacy of dengue vaccine in regions of endemic disease.

OBJECTIVE:To evaluate the association of rainy season with overall dengue disease incidence and with the efficacy of the Sanofi Pasteur recombinant, live, attenuated, tetravalent vaccine (CYD-TDV) in two randomized, controlled multicenter phase III clinical trials in Asia and Latin America. METHODS:...

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Bibliographic Details
Main Authors: Chloé Pasin, M Elizabeth Halloran, Peter B Gilbert, Edith Langevin, R Leon Ochiai, Punnee Pitisuttithum, Maria Rosario Capeding, Gabriel Carrasquilla, Carina Frago, Margarita Cortés, Laurent Chambonneau, Zoe Moodie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0207878

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https://doi.org/10.1371/journal.pone.0207878

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