Alpha-linolenic acid modulates systemic and adipose tissue-specific insulin sensitivity, inflammation, and the endocannabinoid system in dairy cows

Abstract Metabolic disorders are often linked to alterations in insulin signaling. Omega-3 (n-3) fatty acids modulate immunometabolic responses; thus, we examined the effects of peripartum n-3 on systemic and adipose tissue (AT)-specific insulin sensitivity, immune function, and the endocannabinoid...

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Bibliographic Details
Main Authors: Gitit Kra, Jayasimha Rayalu Daddam, Uzi Moallem, Hadar Kamer, Batel Mualem, Yishai Levin, Radka Kočvarová, Alina Nemirovski, Andres G. Contreras, Joseph Tam, Maya Zachut
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32433-7