Non-Invasive O-Toluidine Monitoring during Regional Anaesthesia with Prilocaine and Detection of Accidental Intravenous Injection in an Animal Model

Non-Invasive O-Toluidine Monitoring during Regional Anaesthesia with Prilocaine and Detection of Accidental Intravenous Injection in an Animal Model

Regional anaesthesia is well established as a standard method in clinical practice. Currently, the local anaesthetics of amino-amide types such as prilocaine are frequently used. Despite routine use, complications due to overdose or accidental intravenous injection can arise. A non-invasive method t...

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Bibliographic Details
Main Authors: Beate Brock, Patricia Fuchs, Svend Kamysek, Udo Walther, Selina Traxler, Giovanni Pugliese, Wolfram Miekisch, Jochen K. Schubert, Phillip Trefz
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Metabolites
Subjects:
breath gas analysis
drug monitoring
o-toluidine
prilocaine
PTR-ToF-MS
regional anaesthesia
Online Access:https://www.mdpi.com/2218-1989/12/6/502

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https://www.mdpi.com/2218-1989/12/6/502

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