Escaping mTOR inhibition for cancer therapy: Tumor suppressor functions of mTOR

A master promoter of cell growth, mammalian target of rapamycin (mTOR) is upregulated in a large percentage of cancer cells. Still, targeting mTOR using rapamycin has a limited outcome in patients. Our recent results highlight the additional role of mTOR as a tumor suppressor, explaining these modes...

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Bibliographic Details
Main Authors: Victor H. Villar, Tra Ly Nguyen, Silvia Terés, Clément Bodineau, Raúl V. Durán
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2017.1297284