Maresin1 prevents sepsis-induced acute liver injury by suppressing NF-κB/Stat3/MAPK pathways, mitigating inflammation

Maresin1 prevents sepsis-induced acute liver injury by suppressing NF-κB/Stat3/MAPK pathways, mitigating inflammation

Aims: The treatment of sepsis remains challenging and the liver is a non-neglectful target of sepsis-induced injury. Uncontrolled inflammatory responses exert a central role in the pathophysiological process of sepsis-induced acute liver injury (SI-ALI). Maresin1 (MaR1) is a derivative of omega-3 do...

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Bibliographic Details
Main Authors: Shujun Sun, Li Wang, Jiamei Wang, Rui Chen, Shuaijie Pei, Shanglong Yao, Yun Lin, Chengye Yao, Haifa Xia
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Maresin1 (MaR1)
Sepsis-induced acute liver injury (SI-ALI)
Inflammatory
Cecal ligation and puncture (CLP)
NF-κB/Stat3/MAPK signaling pathways
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023090916

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http://www.sciencedirect.com/science/article/pii/S2405844023090916

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