Successful treatment with adapted high dose methotrexate in a hemodialysis patient with primary central nervous system lymphoma: 100 mg/m2 seems sufficient

Successful treatment with adapted high dose methotrexate in a hemodialysis patient with primary central nervous system lymphoma: 100 mg/m2 seems sufficient

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High dose methotrexate (HD-MTX) based chemoimmunotherapy is a central part of the standard approach to treatment of primary central nervous system lymphoma (PCNSL). Renal dysfunction leads to delayed MTX complete elimination and critical MTX concentration. Despite the recommendations, hemodialysis s...

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Bibliographic Details
Main Authors: Justine Solignac, Laure Farnault, Thomas Robert, Raphaelle Fanciullino, Sylvain Choquet, Philippe Brunet, Geoffroy Venton, Mickaël Bobot
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Nefrología (English Edition)
Subjects:
Metotrexato
Sistema nervioso central
Linfoma
Hemodiálisis
Toxicidad farmacológica
Online Access:http://www.sciencedirect.com/science/article/pii/S2013251422000220

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http://www.sciencedirect.com/science/article/pii/S2013251422000220

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