Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus.

Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus.

Chikungunya virus (CHIKV) is a re-emerging global pathogen with pandemic potential, which causes fever, rash and debilitating arthralgia. Older adults over 65 years are particularly susceptible to severe and chronic CHIKV disease (CHIKVD), accounting for >90% of all CHIKV-related deaths. There ar...

Full description

Bibliographic Details
Main Authors: Jennifer L Uhrlaub, Vesna Pulko, Victor R DeFilippis, Rebecca Broeckel, Daniel N Streblow, Gary D Coleman, Byung S Park, John F Lindo, Ivan Vickers, Joshua J Anzinger, Janko Nikolich-Žugich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-10-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005891&type=printable

Internet

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005891&type=printable

Similar Items