Fasciola hepatica soluble antigens (FhAg) induce ovine PMN innate immune reactions and NET formation in vitro and in vivo

Fasciola hepatica soluble antigens (FhAg) induce ovine PMN innate immune reactions and NET formation in vitro and in vivo

Abstract Fasciola hepatica causes liver fluke disease, a worldwide neglected and re-emerging zoonotic disease, leading to hepatitis in humans and livestock. In the pathogenesis, flukes actively migrate through liver parenchyma provoking tissue damage. Here, parasites must confront leukocytes of the...

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Bibliographic Details
Main Authors: Tamara Muñoz-Caro, Marcela Gómez-Ceruti, Liliana M. R. Silva, Daniel Gutiérrez-Expósito, Henrik Wagner, Anja Taubert, Carlos Hermosilla
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Veterinary Research
Subjects:
Fasciola hepatica
neutrophil extracellular traps
NETosis
ROS
innate immunity
sheep
Online Access:https://doi.org/10.1186/s13567-023-01236-z

Internet

https://doi.org/10.1186/s13567-023-01236-z

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