Computational design and in vitro assay of lantadene-based novel inhibitors of NS3 protease of dengue virus

Computational design and in vitro assay of lantadene-based novel inhibitors of NS3 protease of dengue virus

Dengue virus (DENV) infection is one of the diseases for which no drug is available for the treatment. The DENV NS2B-NS3 protease is considered to be the prime target for anti-dengue drug development because of its importance in the development of new virus subunits via DENV poly-protein breakdown....

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Bibliographic Details
Main Authors: Mujwar Somdutt, Pal Jyoti, Sharma Manu, Tiwari Abhishek, Tiwari Varsha, Kumar Manish, Verma Shivani, Qurtam Ashraf Ahmed, Nasr Fahd A., Al-Zharani Mohammed, Alhalmi Abdulsalam
Format: Article
Language:English
Published: De Gruyter 2024-03-01
Series:Open Chemistry
Subjects:
lantadenes
dengue virus
ns2b-ns3 protease
in silico analysis
Online Access:https://doi.org/10.1515/chem-2024-0004

Internet

https://doi.org/10.1515/chem-2024-0004

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