Evaluation of the inhibition performance of pyrrole derivatives against CYP450 isoforms
Cytochrome P450 is a heme-containing superfamily accountable for the oxidation of various pharmacologically active drugs. The aim of this study was to conduct in silico and in vitro activity assessments of recently synthesized pyrrole-based compounds against three major CYP450 isoforms – CYP1A2, CYP...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Pensoft Publishers
2024-05-01
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Series: | Pharmacia |
Online Access: | https://pharmacia.pensoft.net/article/122067/download/pdf/ |