High expression of BCL6 inhibits the differentiation and development of hematopoietic stem cells and affects the growth and development of chickens

Abstract Background B-cell CLL/lymphoma 6 (BCL6) is a transcriptional master regulator that represses more than 1200 potential target genes. Our previous study showed that a decline in blood production in runting and stunting syndrome (RSS) affected sex-linked dwarf (SLD) chickens compared to SLD ch...

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Bibliographic Details
Main Authors: Hongmei Li, Bowen Hu, Shang Hu, Wen Luo, Donglei Sun, Minmin Yang, Zhiying Liao, Haohui Wei, Changbin Zhao, Dajian Li, Meiqing Shi, Qingbin Luo, Dexiang Zhang, Qinghua Nie, Xiquan Zhang
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s40104-020-00541-3