Locally-Delivered T-Cell-Derived Cellular Vehicles Efficiently Track and Deliver Adenovirus Delta24-RGD to Infiltrating Glioma

Locally-Delivered T-Cell-Derived Cellular Vehicles Efficiently Track and Deliver Adenovirus Delta24-RGD to Infiltrating Glioma

Oncolytic adenoviral vectors are a promising alternative for the treatment of glioblastoma. Recent publications have demonstrated the advantages of shielding viral particles within cellular vehicles (CVs), which can be targeted towards the tumor microenvironment. Here, we studied T-cells, often havi...

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Bibliographic Details
Main Authors: Rutger K. Balvers, Zineb Belcaid, Sanne K. van den Hengel, Jenneke Kloezeman, Jeroen de Vrij, Hiroaki Wakimoto, Rob C. Hoeben, Reno Debets, Sieger Leenstra, Clemens Dirven, Martine L.M. Lamfers
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Viruses
Subjects:
glioblastoma
oncolytic
cellular vehicles
GSC
T-cell therapy
virotherapy
Delta24-RGD
Online Access:http://www.mdpi.com/1999-4915/6/8/3080

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http://www.mdpi.com/1999-4915/6/8/3080

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