Exploration of the influence of KHDC3L gene knock-out by CRISPR/Cas9 technology on PEG3 promoter

Exploration of the influence of KHDC3L gene knock-out by CRISPR/Cas9 technology on PEG3 promoter

Background and aim: CRISPR-Cas9, enable precise DNA manipulation via RNA-guided breaks. KHDC3L and PEG3 genes are vital; CRISPR-Cas9 studies their roles in reproduction, development, and gene regulation. Focusing on KHDC3L's impact on PEG3 promoter in HCT116 cells, insights into gene functions...

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Bibliographic Details
Main Authors: Arezoo Jokar, Shayan Khalili Alashti, Maryam Baneshi, Ali Rastegarian, Kimia Sadat Hashemi, Mohadese Koohi Aliabadi, Mojtaba Kashfi, amir savardashtaki
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2023-12-01
Series:Trends in Pharmaceutical Sciences
Subjects:
khdc3l gene
peg3 promoter
crispr/cas9
gene knock-out
Online Access:https://tips.sums.ac.ir/article_49730_569136271724191afa9f85fcec28bc47.pdf

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https://tips.sums.ac.ir/article_49730_569136271724191afa9f85fcec28bc47.pdf

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