Molecular interactions between metformin and D-limonene inhibit proliferation and promote apoptosis in breast and liver cancer cells

Molecular interactions between metformin and D-limonene inhibit proliferation and promote apoptosis in breast and liver cancer cells

Abstract Background Cancer is a fatal disease that severely affects humans. Designing new anticancer strategies and understanding the mechanism of action of anticancer agents is imperative. Hypothesis/Purpose In this study, we evaluated the utility of metformin and D-limonene, alone or in combinatio...

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Bibliographic Details
Main Authors: Elsayed I. Salim, Mona M. Alabasy, Eman M. El Nashar, Norah S. Al-Zahrani, Mohammed A. Alzahrani, Zihu Guo, Doha M. Beltagy, Mohamed Shahen
Format: Article
Language:English
Published: BMC 2024-05-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Metformin
D-limonene
HepG2
MCF-7
Drug–target–pathway network
Gene analysis
Online Access:https://doi.org/10.1186/s12906-024-04453-x

Internet

https://doi.org/10.1186/s12906-024-04453-x

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