Cisplatin's dual-effect on the circadian clock triggers proliferation and apoptosis

The circadian clock, which generates the internal daily rhythm largely mediated through release of melatonin, can be disrupted in various ways. Multiple factors result in a disruption of the circadian cycle in the clinical context, of interest are anti-cancer drugs such as cisplatin. Cisplatin modul...

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Bibliographic Details
Main Authors: Zuhair Sadiq, Elizabeth Varghese, Dietrich Büsselberg
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Neurobiology of Sleep and Circadian Rhythms
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451994420300067