Inflammasomes in Alzheimer’s Progression: Nrf2 as a Preventive Target

Current knowledge about Alzheimer’s disease highlights the accumulation of β-amyloid plaques (Aβ1–42) and neurofibrillary tangles composed of hyperphosphorylated Tau, which lead to the loss of neuronal connections. Microglial activation and the release of inflammatory mediators play a significant ro...

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Bibliographic Details
Main Authors: Rubén López-Hernández, María Magdalena de la Torre-Álamo, Belén García-Bueno, Alberto Baroja-Mazo, Francisco Jose Fenoy, Santiago Cuevas
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/14/2/121