Characterization of phage resistance and phages capable of intestinal decolonization of carbapenem-resistant Klebsiella pneumoniae in mice

Fang et al. characterized two previously unidentified phage species that could inhibit growth and decrease virulence of carbapenem-resistant Klebsiella pneumoniae (CRKP). They also showed that CRKP develop phage resistance but could still be decolonized in a mouse intestinal colonization model, high...

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Bibliographic Details
Main Authors: Qingqing Fang, Yu Feng, Alan McNally, Zhiyong Zong
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03001-y