MiRNA expression may account for chronic but not for acute regulation of mRNA expression in human thyroid tumor models.

BACKGROUND: For thyroid tumorigenesis, two main human in vitro models are available: primary cultures of human thyrocytes treated with TSH or EGF/serum as models for autonomous adenomas (AA) or papillary thyroid carcinomas (PTC) respectively, and human thyroid tumor derived cell lines. Previous work...

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Bibliographic Details
Main Authors: Sébastien L Floor, Aline Hebrant, Jaime M Pita, Manuel Saiselet, Christophe Trésallet, Frederick Libert, Guy Andry, Jacques E Dumont, Wilma C van Staveren, Carine Maenhaut
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4222942?pdf=render