Mitochondria-targeted triphenylphosphonium-based compounds do not affect estrogen receptor α
Background Targeting negatively charged mitochondria is often achieved using triphenylphosphonium (TPP) cations. These cationic vehicles may possess biological activity, and a docking study indicates that TPP-moieties may act as modulators of signaling through the estrogen receptor α (ERα). Moreover...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2020-03-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/8803.pdf |