Mitochondria-targeted triphenylphosphonium-based compounds do not affect estrogen receptor α

Background Targeting negatively charged mitochondria is often achieved using triphenylphosphonium (TPP) cations. These cationic vehicles may possess biological activity, and a docking study indicates that TPP-moieties may act as modulators of signaling through the estrogen receptor α (ERα). Moreover...

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Bibliographic Details
Main Authors: Ludmila A. Zinovkina, Alina K. Galivondzhyan, Anastasia S. Prikhodko, Ivan I. Galkin, Roman A. Zinovkin
Format: Article
Language:English
Published: PeerJ Inc. 2020-03-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/8803.pdf