Gestational Caloric Restriction Alters Adipose Tissue Methylome and Offspring’s Metabolic Profile in a Swine Model

Gestational Caloric Restriction Alters Adipose Tissue Methylome and Offspring’s Metabolic Profile in a Swine Model

Limited nutrient supply to the fetus results in physiologic and metabolic adaptations that have unfavorable consequences in the offspring. In a swine animal model, we aimed to study the effects of gestational caloric restriction and early postnatal metformin administration on offspring’s adipose tis...

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Bibliographic Details
Main Authors: Berta Mas-Parés, Sílvia Xargay-Torrent, Gemma Carreras-Badosa, Ariadna Gómez-Vilarrubla, Maria Niubó-Pallàs, Joan Tibau, Josep Reixach, Anna Prats-Puig, Francis de Zegher, Lourdes Ibañez, Judit Bassols, Abel López-Bermejo
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
caloric restriction
metabolic programing
DNA methylation
adipose tissue
Online Access:https://www.mdpi.com/1422-0067/25/2/1128

Internet

https://www.mdpi.com/1422-0067/25/2/1128

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