Comparison of Quantitative Real-Time PCR and Digital PCR to Detect the Polyomavirus in Merkel Cell Carcinoma

Comparison of Quantitative Real-Time PCR and Digital PCR to Detect the Polyomavirus in Merkel Cell Carcinoma

Merkel cell polyomavirus (MCPyV) prevalence in Merkel cell carcinoma (MCC) cases is controversial. The detection and quantification of MCPyV DNA is mainly performed by PCR techniques using formalin-fixed, paraffin-embedded (FFPE) tissues. The aim of this study is to compare the performance of two di...

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Bibliographic Details
Main Authors: Martina Barchitta, Andrea Maugeri, Elisabetta Campisi, Roberta Magnano San Lio, Giuliana Favara, Hector Jose Soto Parra, Lucia Salvatorelli, Gaetano Magro, Guido Basile, Antonella Agodi
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
Merkel cell polyomavirus
Merkel cell carcinoma
FFPE skin samples
real-time qPCR
digital PCR
Online Access:https://www.mdpi.com/1999-4915/14/10/2195

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https://www.mdpi.com/1999-4915/14/10/2195

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