M3 subtype of muscarinic acetylcholine receptor promotes cardioprotection via the suppression of miR-376b-5p.

The M(3) subtype of muscarinic acetylcholine receptors (M(3)-mAChR) plays a protective role in myocardial ischemia and microRNAs (miRNAs) participate in many cardiac pathophysiological processes, including ischemia-induced cardiac injury. However, the role of miRNAs in M(3)-mAChR mediated cardioprot...

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Main Authors: Zhenyu Pan, Yueping Guo, Hanping Qi, Kai Fan, Shu Wang, Hua Zhao, Yuhua Fan, Jing Xie, Feng Guo, Yunlong Hou, Ning Wang, Rong Huo, Yong Zhang, Yan Liu, Zhimin Du
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3292572?pdf=render