Conditioned culture medium of bone marrow mesenchymal stem cells promotes phenotypic transformation of microglia by regulating mitochondrial autophagy

Objective To study the mechanism by which conditioned medium of bone marrow mesenchymal stem cells (BMSCs-CM) facilitates the transition of pro-inflammatory polarized microglia to an anti-inflammatory phenotype. Methods BV2 cells, a mouse microglia cell line, were transformed into a pro-inflammatory...

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Bibliographic Details
Main Authors: Hangyu Ji, Weiming Chu, Yong Yang, Xin Peng, Xiaoli Song
Format: Article
Language:English
Published: PeerJ Inc. 2024-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/17664.pdf