Effects of Restoration of Blood Flow on the Development of Aortic Atherosclerosis in ApoE−/− Mice With Unilateral Renal Artery Stenosis

Effects of Restoration of Blood Flow on the Development of Aortic Atherosclerosis in ApoE−/− Mice With Unilateral Renal Artery Stenosis

BackgroundChronic unilateral renal artery stenosis (RAS) causes accelerated atherosclerosis in apolipoprotein E–deficient (ApoE−/−) mice, but effects of restoration of renal blood flow on aortic atherosclerosis are unknown. Methods and ResultsMale ApoE−/− mice underwent sham surgery (n=16) or had pa...

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Bibliographic Details
Main Authors: Alokkumar S. Pathak, Jianhua Huang, Mauricio Rojas, Taylor C. Bazemore, Ruihai Zhou, George A. Stouffer
Format: Article
Language:English
Published: Wiley 2016-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atherosclerosis
hypertension
inflammation
renal
renal artery stenosis
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.115.002953

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.115.002953

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