Digital spatial profiling identifies molecular changes involved in development of colitis-associated colorectal cancer

Digital spatial profiling identifies molecular changes involved in development of colitis-associated colorectal cancer

ObjectiveChronic colonic inflammation seen in inflammatory bowel disease (IBD) is a risk factor for colorectal cancer (CRC). Colitis-associated cancers (CAC) are molecularly different from sporadic CRC. This study aimed to evaluate spatially defined molecular changes associated with neoplastic progr...

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Bibliographic Details
Main Authors: Tamara Glyn, Sarah Williams, Martin Whitehead, Tim Eglinton, Nicholas West, Rachel V. Purcell
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Oncology
Subjects:
colorectal (colon) cancer
IBD - inflammatory bowel disease
inflammation
spatial gene expression
colitis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1247106/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2024.1247106/full

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