Digital spatial profiling identifies molecular changes involved in development of colitis-associated colorectal cancer

Digital spatial profiling identifies molecular changes involved in development of colitis-associated colorectal cancer

ObjectiveChronic colonic inflammation seen in inflammatory bowel disease (IBD) is a risk factor for colorectal cancer (CRC). Colitis-associated cancers (CAC) are molecularly different from sporadic CRC. This study aimed to evaluate spatially defined molecular changes associated with neoplastic progr...

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Bibliographic Details
Main Authors:	Tamara Glyn, Sarah Williams, Martin Whitehead, Tim Eglinton, Nicholas West, Rachel V. Purcell
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Series:	Frontiers in Oncology
Subjects:	colorectal (colon) cancer IBD - inflammatory bowel disease inflammation spatial gene expression colitis
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1247106/full

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