Aryl Hydrocarbon Receptor Regulates Muc2 Production Independently of IL-22 during Colitis

Aryl Hydrocarbon Receptor Regulates Muc2 Production Independently of IL-22 during Colitis

We previously reported that an aryl hydrocarbon receptor (AhR) ligand, indole-3-carbinol (I3C), was effective at reducing colitis severity through immune cell-mediated interleukin-22 (IL-22) production. Intestinal epithelial cells (IECs) are also involved in regulating colitis, so we investigated th...

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Bibliographic Details
Main Authors: Archana Saxena, Chandani Mitchell, Raymond Bogdon, Kasie Roark, Kiesha Wilson, Shanieka Staley, Michelle Hailey, Michal Claire Williams, Alex Rutkovsky, Prakash Nagarkatti, Mitzi Nagarkatti, Philip Brandon Busbee
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
inflammatory bowel disease
colitis
aryl hydrocarbon receptor
indole-3-carbinol
mucin
interleukin-22
Online Access:https://www.mdpi.com/1422-0067/25/4/2404

Internet

https://www.mdpi.com/1422-0067/25/4/2404

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