Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen

ABSTRACT The blood-brain barrier (BBB) protects the central nervous system (CNS) by restricting the passage of molecules and microorganisms. Despite this barrier, however, the fungal pathogen Cryptococcus neoformans invades the brain, causing a meningoencephalitis that is estimated to kill over 600,...

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Bibliographic Details
Main Authors: Felipe H. Santiago-Tirado, Michael D. Onken, John A. Cooper, Robyn S. Klein, Tamara L. Doering
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.02183-16