Copy number footprints of platinum-based anticancer therapies.

Recently, distinct mutational footprints observed in metastatic tumors, secondary malignancies and normal human tissues have been demonstrated to be caused by the exposure to several chemotherapeutic drugs. These characteristic mutations originate from specific lesions caused by these chemicals to t...

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Bibliographic Details
Main Authors: Santiago Gonzalez, Nuria Lopez-Bigas, Abel Gonzalez-Perez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010634