Microarray analysis identifies defects in regenerative and immune response pathways in COPD airway basal cells

Background Airway basal cells are specialised stem cells and regenerate airway epithelium. Airway basal cells isolated from patients with COPD regenerate airway epithelium with an abnormal phenotype. We performed gene expression analysis to gain insights into the defective regenerative programme in...

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Bibliographic Details
Main Authors: Fanny Pineau, Gabriella Shumyatsky, Nicole Owuor, Nisha Nalamala, Sudhir Kotnala, Sudhir Bolla, Nathaniel Marchetti, Steven Kelsen, Gerard J. Criner, Uma S. Sajjan
Format: Article
Language:English
Published: European Respiratory Society 2020-12-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/6/4/00656-2020.full