Relation between body composition and severe diarrhea in patients treated with preoperative chemoradiation with capecitabine for rectal cancer: a single-centre cohort study

Abstract Background Chemoradiation with capecitabine followed by surgery is standard care for locally advanced rectal cancer (LARC). Severe diarrhea is considered a dose-limiting toxicity of adding capecitabine to radiation therapy. The aim of this study was to describe the risk factors and the impa...

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Bibliographic Details
Main Authors: J. M. van Rees, W. Hartman, J. J. M. E. Nuyttens, E. Oomen-de Hoop, J. L. A. van Vugt, J. Rothbarth, C. Verhoef, E. van Meerten
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Gastroenterology
Subjects:
Online Access:https://doi.org/10.1186/s12876-021-01886-3