The MAP3K7-mTOR Axis Promotes the Proliferation and Malignancy of Hepatocellular Carcinoma Cells

Targeted therapy is currently limited for patients with hepatocellular carcinoma (HCC) due to the lack of suitable targets. Kinases play pivotal roles in many cellular biological processes, whereas dysregulation of kinases may lead to various diseases, particularly cancer. However, the role of kinas...

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Bibliographic Details
Main Authors: Jin-Shiung Cheng, Wei-Lun Tsai, Pei-Feng Liu, Yih-Gang Goan, Chih-Wen Lin, Ho-Hsing Tseng, Cheng-Hsin Lee, Chih-Wen Shu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00474/full