Metabolomics coupled with multivariate data and pathway analysis on potential biomarkers in cholestasis and intervention effect of Paeonia lactiflora Pall.

Metabolomics coupled with multivariate data and pathway analysis on potential biomarkers in cholestasis and intervention effect of Paeonia lactiflora Pall.

Background: The dried root of Paeonia lactiflora Pall. (PLP) is a classical Chinese herbal medicine that has been used to treat hepatic disease for thousands of years. Our previous work suggested that PLP can be used to treat hepatitis with severe cholestasis. This study explored the mechanism by wh...

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Bibliographic Details
Main Authors: Xiao eMa, Yong-Hui eChi, Ming eNiu, Yun eZhu, Yan-Ling eZhao, Zhe eChen, Jia-Bo eWang, Cong-En eZhang, Jian-Yu eLi, Li-Fu eWang, Man eGong, Shi-Zhang eWei, Chang eChen, Lu eZhang, Ming-Quan eWu, Xiao-He eXiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Pharmacology
Subjects:
Cholestasis
Metabolomics
biomarker
Paeonia lactiflora Pall.
Bile acid secretion
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00014/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00014/full

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