Asymmetric Localization of Cdx2 mRNA during the First Cell-Fate Decision in Early Mouse Development

A longstanding question in mammalian development is whether the divisions that segregate pluripotent progenitor cells for the future embryo from cells that differentiate into extraembryonic structures are asymmetric in cell-fate instructions. The transcription factor Cdx2 plays a key role in the fir...

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Bibliographic Details
Main Authors: Maria Skamagki, Krzysztof B. Wicher, Agnieszka Jedrusik, Sujoy Ganguly, Magdalena Zernicka-Goetz
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713000132