Asymmetric Localization of Cdx2 mRNA during the First Cell-Fate Decision in Early Mouse Development
A longstanding question in mammalian development is whether the divisions that segregate pluripotent progenitor cells for the future embryo from cells that differentiate into extraembryonic structures are asymmetric in cell-fate instructions. The transcription factor Cdx2 plays a key role in the fir...
Main Authors: | Maria Skamagki, Krzysztof B. Wicher, Agnieszka Jedrusik, Sujoy Ganguly, Magdalena Zernicka-Goetz |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-02-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124713000132 |
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