Female Sex but Not Oestrogen Receptor Expression Predicts Survival in Advanced Gastroesophageal Adenocarcinoma—A Post-hoc Analysis of the GO2 Trial

Female Sex but Not Oestrogen Receptor Expression Predicts Survival in Advanced Gastroesophageal Adenocarcinoma—A Post-hoc Analysis of the GO2 Trial

Gastroesophageal adenocarcinoma is a disease of older adults that is associated with a very poor prognosis. It is less common and has better outcomes in females. The reason for this is unknown but may relate to signalling via the main oestrogen receptors (ER) α and β. In this study, we sought to inv...

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Bibliographic Details
Main Authors: Mark A. Baxter, Lindsay C. Spender, Shaun Walsh, Susan Bray, Gemma Skinner, Sharon King, Peter S. Hall, Matthew J. Seymour, Russell D. Petty, on behalf of the GO2 Investigators
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cancers
Subjects:
gastroesophageal cancer
oestrogen receptor
older adults
prognosis
biomarker
Online Access:https://www.mdpi.com/2072-6694/15/9/2591

Internet

https://www.mdpi.com/2072-6694/15/9/2591

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