Sequential activation of M1 and M2 phenotypes in macrophages by Mg degradation from Ti-Mg alloy for enhanced osteogenesis

Abstract Background Even though the modulatory effects of Magnisum (Mg) and its alloys on bone-healing cells have been widely investigated during the last two decades, relatively limited attention has been paid on their inflammation-modulatory properties. Understanding the activation process of macr...

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Bibliographic Details
Main Authors: Luxin Liang, Deye Song, Kai Wu, Zhengxiao Ouyang, Qianli Huang, Guanghua Lei, Kun Zhou, Jian Xiao, Hong Wu
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-04-01
Series:Biomaterials Research
Subjects:
Online Access:https://doi.org/10.1186/s40824-022-00262-w