Use of Capsaicin to Treat Pain: Mechanistic and Therapeutic Considerations

Capsaicin is the pungent ingredient of chili peppers and is approved as a topical treatment of neuropathic pain. The analgesia lasts for several months after a single treatment. Capsaicin selectively activates TRPV1, a Ca2+-permeable cationic ion channel that is enriched in the terminals of certain...

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Bibliographic Details
Main Authors: Man-Kyo Chung, James N. Campbell
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/9/4/66