Using a pan-cancer atlas to investigate tumour associated macrophages as regulators of immunotherapy response

Abstract The paradigm for macrophage characterization has evolved from the simple M1/M2 dichotomy to a more complex model that encompasses the broad spectrum of macrophage phenotypic diversity, due to differences in ontogeny and/or local stimuli. We currently lack an in-depth pan-cancer single cell...

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Bibliographic Details
Main Authors: Alexander Coulton, Jun Murai, Danwen Qian, Krupa Thakkar, Claire E. Lewis, Kevin Litchfield
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-49885-8