AIRE is a critical spindle-associated protein in embryonic stem cells

Embryonic stem (ES) cells go though embryo-like cell cycles regulated by specialized molecular mechanisms. However, it is not known whether there are ES cell-specific mechanisms regulating mitotic fidelity. Here we showed that Autoimmune Regulator (Aire), a transcription coordinator involved in immu...

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Bibliographic Details
Main Authors: Bin Gu, Jean-Philippe Lambert, Katie Cockburn, Anne-Claude Gingras, Janet Rossant
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/28131