Utility of a PI3K/mTOR inhibitor (NVP-BEZ235) for thyroid cancer therapy.

Utility of a PI3K/mTOR inhibitor (NVP-BEZ235) for thyroid cancer therapy.

BACKGROUND: We assessed the utility of the dual PI3K/mTOR inhibitor NVP-BEZ235 (BEZ235) as single agent therapy and in combination with conventional chemotherapy for thyroid cancer. METHODOLOGY/PRINCIPAL FINDINGS: Eight cell lines from four types of thyroid cancer (papillary, follicular, anaplastic,...

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Bibliographic Details
Main Authors: Shu-Fu Lin, Yu-Yao Huang, Jen-Der Lin, Ting-Chao Chou, Chuen Hsueh, Richard J Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471922?pdf=render

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http://europepmc.org/articles/PMC3471922?pdf=render

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