Network pharmacology and experimental evidence reveal the protective mechanism of Yi-Qi Cong-Ming decoction on age-related hearing loss

Network pharmacology and experimental evidence reveal the protective mechanism of Yi-Qi Cong-Ming decoction on age-related hearing loss

Context Yi-Qi Cong-Ming (YQCM) decoction has been widely used to prevent age-related hearing loss (ARHL), the most prevalent neurodegenerative disease in the elderly.Objective To explore the mechanism of YQCM decoction in the treatment of ARHL.Materials and methods The chemical constituents of YQCM...

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Bibliographic Details
Main Authors: Yi-Fang Yang, Xi-Rui Yan, Rui-Xin Wu, Ning Li, Min Chu, Yang Dong, Shu-Ping Fu, Jian-Rong Shi, Qing Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Pharmaceutical Biology
Subjects:
Molecular docking
molecular dynamics simulation
HEI-OC1
apoptosis
mitochondrial membrane potential
AKT1
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2022.2101671

Internet

https://www.tandfonline.com/doi/10.1080/13880209.2022.2101671

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