Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies
Serum and glucocorticoid-regulated kinase 1 (SGK1) is a serine/threonine kinase that works under acute transcriptional control by several stimuli, including serum and glucocorticoids. It plays a significant role in the cancer progression and metastasis, as it regulates inflammation, apoptosis, hormo...
Autors principals: | , , , , , , , |
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Format: | Article |
Idioma: | English |
Publicat: |
MDPI AG
2020-02-01
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Col·lecció: | Molecules |
Matèries: | |
Accés en línia: | https://www.mdpi.com/1420-3049/25/4/823 |