Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies
Serum and glucocorticoid-regulated kinase 1 (SGK1) is a serine/threonine kinase that works under acute transcriptional control by several stimuli, including serum and glucocorticoids. It plays a significant role in the cancer progression and metastasis, as it regulates inflammation, apoptosis, hormo...
Главные авторы: | , , , , , , , |
---|---|
Формат: | Статья |
Язык: | English |
Опубликовано: |
MDPI AG
2020-02-01
|
Серии: | Molecules |
Предметы: | |
Online-ссылка: | https://www.mdpi.com/1420-3049/25/4/823 |