Thioredoxin priming prolongs lung allograft survival by promoting immune tolerance.

Thioredoxin priming prolongs lung allograft survival by promoting immune tolerance.

Tolerance to allograft antigen is the major challenge and final goal of transplant medicine. Our previous study demonstrated that thioredoxin-1 (Trx) priming of donor lung significantly protected allogeneic lung graft. To determine whether Trx priming of donor lung inhibits allograft rejection, exte...

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Bibliographic Details
Main Authors: Hanbo Hu, Xiaoyan Zhu, Sunil Joshi, Li Lu, Chang-Qing Xia, Jawaharlal M Patel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4416780?pdf=render

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http://europepmc.org/articles/PMC4416780?pdf=render

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