Targeting triple-negative breast cancer cells with a β1-integrin binding aptamer

Targeting triple-negative breast cancer cells with a β1-integrin binding aptamer

Targeted therapies have increased the treatment options for triple-negative breast cancer patients. However, the paucity of targetable biomarkers and tumor heterogeneity have limited the ability of precision-guided interventions to live up to their full potential. As affinity-targeting ligands, apta...

Full description

Bibliographic Details
Main Authors: Karlis Pleiko, Maarja Haugas, Vadims Parfejevs, Teodors Pantelejevs, Emilio Parisini, Tambet Teesalu, Una Riekstina
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Oligonucleotides: Therapies and Applications
aptamer
β1-integrin
aptamer internalization
proximity labeling
affinity ligands
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123002263

Internet

http://www.sciencedirect.com/science/article/pii/S2162253123002263

Similar Items